For many years now, PharmaCaribe has been providing Hypertonic Saline to help with sputum induction where sputum production is indicated.
PulmoSal 7% (pH+) is a 2nd Generation Bio-Balanced™ Hypertonic Saline. We combined the clinically proven 7% hypertonic saline concentration with a pH of 7.4 which is the physiologic pH of healthy respiratory systems (ref: PharmaCaribe Press Release 2013).
At NACFC 2014 a poster presentation comparing Hypertonic Saline made to USP and PulmoSal 7% (pH+) concludes that “These data show approximately 5 log decrease in bacterial density in the pH 7.4 solution compared with approximately 2 log decrease in the two commercially available HS’s having pH 5.86 and pH 6.60 solutions at 24 hours”. (ref: “pH-dependent differential Pseudomonas Aeruginosa Killing in CF Sputum incubated in hypertonic saline solutions”)